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Antigen Retrieval Immunohistochemistry Based Research and Diagnostics

Wiley, J,
E-Book ( PDF mit Adobe DRM )
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The most complete, up-to-date reference on antigen retrieval andimmunohistochemistry
An antigen is a substance that prompts the generation ofantibodies and can cause an immune response. The antigen retrieval(AR) technique is in wide use across the globe, and is a criticaltechnique used in medical diagnosis of disease, particularlyclinical targeted cancer treatment.
Antigen Retrieval Immunohistochemistry Based Research andDiagnostics discusses several scientific approaches to thestandardization of quantifiable immunohistochemistry (IHC). Basedon the development and application of AR by the editors, thisvolume summarizes recent achievements in AR-IHC and analyzesnumerous cutting-edge issues for future research projects.
Featuring contributions from a worldwide group of leadingexperts and research scientists in the field, this importantwork:
* Summarizes the key problems in the four fields of antigenretrieval
* Discusses the advances of AR techniques and theirapplications
* Provides practical methods and protocols in AR-IHC, such asextraction of nucleic acids and proteins for molecular analysis,cell/tissue sample preparation, and standardization and developmentof various techniques to meet the future needs of¿clinical andresearch molecular analysis
* Encourages further research in AR and IHC, particularly how ARmethods might be employed for improved test performance and thedevelopment of greater reliability and reproducibility of IHC
* Includes an appendix of related laboratory protocols
Antigen Retrieval Immunohistochemistry Based Research andDiagnostics is intended for clinical pathologists, molecularcell biologists, basic research scientists, technicians, andgraduate students who undertake tissue/cell morphologic andmolecular analysis and wish to use and extend the power ofimmunohistochemistry. It is also pertinent for most biotechnologycompanies majoring in development of IHC products.
Wiley Series in Biomedical Engineering and Multi-DisciplinaryIntegrated Systems / Kai Chang, Series Editor


Titel: Antigen Retrieval Immunohistochemistry Based Research and Diagnostics
Autoren/Herausgeber: Shan-Rong Shi, Clive R. Taylor (Hrsg.)
Aus der Reihe: Wiley Series in Biomedical Engineering
Ausgabe: 1. Auflage

ISBN/EAN: 9780470875605

Seitenzahl: 420
Produktform: E-Book
Sprache: Englisch

Shan-Rong Shi, MD, is professor of clinical pathology at theKeck School of Medicine of the University of Southern California.He is the Associate Editor of The Journal of Histochemistry andcytochemistry, he is on the Editoral Board of AppliedImmunohistochemistry and Molecular Morphology and is also on theOverseas Editorial Board of the Chinese Journal of Pathology. Dr.Shi is the ineventor of the antigen retrieval (AR) technique.
Clive R. Taylor, MD, PhD, is Senior Associate Dean,Professor and Chairman of Pathology at the Keck School of Medicine.Dr. Taylor is Editor in Chief of Applied Immunohistochemistry andMolecular Morphology. Dr. Taylor is a world renowned expert inimmunohistochemistry and clinical pathology. - Newsletter
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