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Dynamic Combinatorial Chemistry

In Drug Discovery, Bioorganic Chemistry, and Materials Science

Wiley, J,
E-Book ( PDF mit Adobe DRM )
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Effective techniques for applying Dynamic CombinatorialChemistry
In a relatively short period, Dynamic Combinatorial Chemistry(DCC) has grown from proof-of-concept experiments in a few isolatedlabs to a broad conceptual framework with applications to anexceptional range of problems in molecular recognition, leadcompound identification, catalyst design, nanotechnology, polymerscience, and others. Bringing together a group of respectedexperts, this overview explains how chemists can apply DCC andfragment-based library methods to lead generation for drugdiscovery and molecular recognition in bioorganic chemistry andmaterials science.
Chapters cover:
* Basic theory
* Approaches to binding in proteins and nucleic acids
* Molecular recognition
* Self-sorting
* Catalyst discovery
* Materials discovery
* Analytical chemistry challenges
A comprehensive, single-source reference about DCC methods andapplications including aspects of fragment-based drug discovery,this is a core reference that will spark the development of newsolutions and strategies for chemists building structure librariesand designing compounds and materials.


Titel: Dynamic Combinatorial Chemistry
Autoren/Herausgeber: Benjamin L. Miller (Hrsg.)
Ausgabe: 1. Auflage

ISBN/EAN: 9780470551547

Seitenzahl: 240
Produktform: E-Book
Sprache: Englisch

Benjamin L. Miller is an Associate Professor of Dermatology, Biomedical Engineering, and Biochemistry and Biophysics at the University of Rochester. In addition to his academic credentials, Dr. Miller has industry consulting experience as the founder of Adarza BioSystems and Lighthouse Biosciences. - Newsletter
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