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Flexible Viruses

Structural Disorder in Viral Proteins

Wiley, J,
E-Book ( EPUB mit Adobe DRM )
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This book provides up-to-date information on experimental and computational characterization of the structural and functional properties of viral proteins, which are widely involved in regulatory and signaling processes. With chapters by leading research groups, it features current information on the structural and functional roles of intrinsic disorders in viral proteomes. It systematically addresses the measles, HIV, influenza, potato virus, forest virus, bovine virus, hepatitis, and rotavirus as well as viral genomics. After analyzing the unique features of each class of viral proteins, future directions for research and disease management are presented.


Titel: Flexible Viruses
Autoren/Herausgeber: Vladimir Uversky, Sonia Longhi
Aus der Reihe: Wiley Series in Protein and Peptide Science
Ausgabe: 1. Auflage

ISBN/EAN: 9781118135563

Seitenzahl: 500
Produktform: E-Book
Sprache: Englisch

VLADIMIR N. UVERSKY is an Associate Professor at the Departmentof Molecular Medicine at the University of South Florida (USF). Heobtained his academic degrees from Moscow Institute of Physics andTechnology (PhD in 1991) and from the Institute of Experimental andTheoretical Biophysics, Russian Academy of Sciences (DSc in 1998).He spent his early career working mostly on protein folding at theInstitute of Protein Research and Institute for BiologicalInstrumentation, Russia. In 1998, he moved to the University ofCalifornia Santa Cruz where for six years he was studying proteinfolding, misfolding, protein conformation diseases, and proteinintrinsic disorder phenomenon. In 2004, he was invited to join theIndiana University School of Medicine as a Senior ResearchProfessor to work on intrinsically disordered proteins. Since 2010,Professor Uversky is with USF, where he continues to studyintrinsically disordered proteins and protein folding andmisfolding processes. He has authored over 400 scientificpublications and edited several books and book series on proteinstructure, function, folding and misfolding.
SONIA LONGHI is a Director of Research at the Center for theNational Scientific Research (CNRS). She obtained her academicdegree (PhD) from the University of Milan in 1993. She then went tothe Architecture and Function of Biological Macromoleculeslaboratory (AFMB, UMR 6098, CNRS and Aix-Marseille University)where she did postdoctoral work on protein crystallography. Since2006, she has been heading the "Structural Disorder and MolecularRecognition" group within the AFMB laboratory. She has authoredmore than 70 scientific publications and edited a book on measlesvirus nucleoprotein and coedited, with Prof. Vladimir Uversky, abook entitled Instrumental Analysis of Intrinsically DisorderedProteins (Wiley).

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