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Frontiers of Cord Blood Science

Springer London,
Buch
203,29 € Lieferbar in 5-7 Tagen
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This innovative book contains chapters from distinguished investigators engaged in researching cord blood in the treatment of various diseases of the brain, heart, liver, pancreas, bone and cartilage. The current state of research in the field is presented.

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Hauptbeschreibung

Titel: Frontiers of Cord Blood Science
Autoren/Herausgeber: Niranjan Bhattacharya, Phillip Stubblefield (Hrsg.)
Ausgabe: Softcover reprint of hardcover 1st ed. 2009

ISBN/EAN: 9781849967426

Seitenzahl: 400
Format: 23,5 x 15,5 cm
Produktform: Taschenbuch/Softcover
Gewicht: 635 g
Sprache: Englisch

Cord blood is a significant source of hematopoietic stem and progenitor cells for the treatment of blood and genetic disorders. Cord blood is also an alternative to embryos as a source of tissue for regenerative medicine. Cells from cord blood have been shown to transdifferentiate into nonhematopoietic cells, including those of the brain, heart, liver, pancreas, bone, and cartilage, in tissue culture and in animal systems. Recently it has been demonstrated that both cardiac and glial cell differentiation of cord blood donor cells occurred in recipients of unrelated donor cord blood transplantation as part of a treatment regime for Krabbe disease and Sanfilippo syndrome. These observations raise the possibility that cord blood may serve as a source of cells to facilitate tissue repair and regeneration in the future. CD34 stem cell-rich umbilical cord whole blood transfusion has the potential to have an immediate benefit of better tissue oxygenation with an additional delayed benefit of possible engraftment of umbilical cord stem cells.

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