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Gene Therapy

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Gene Therapy presents a comprehensive overview of the field, ranging from vector development and therapeutic gene selection to the results of the most recent clinical trials. Written in a clear, didactic style, the volume makes gene therapy methods easily accessible to readers.

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Titel: Gene Therapy
Autoren/Herausgeber: Mauro Giacca
Ausgabe: 2010

ISBN/EAN: 9788847055551

Seitenzahl: 303
Format: 23,5 x 15,5 cm
Produktform: Taschenbuch/Softcover
Gewicht: 504 g
Sprache: Englisch

Mauro Giacca, MD, PhD, is the Director of the Italian Component of the International Centre for Genetic Engineering and Biotechnology (ICGEB), an international research organisation based in Trieste, Italy, and full professor of molecular biology at the Faculty of Medicine of the University of Trieste. Over the last 20 years, he has participated in the front line in the development of the gene therapy field. He is internationally recognized as an expert in AAV vector biology and in the application of AAV vectors for the gene therapy of cardiovascular disorders.

I entered the gene therapy field in the mid-1990s, being fascinated by the immense potential of genes as drugs for the treatment of human disease. Since then, I have experienced the ups and downs of this discipline, and tried to contribute with my work and that of my laboratory to the development of innovative approaches to the treatment of cardiovascular disorders. During these years, I have had several opp- tunities to speak on gene therapy at lectures and academic lessons, and have often noticed that the field is very attractive to scientists of all disciplines. However, as yet no comprehensive book on the subject has been published. Indeed, most books in the field are either a collection of gene transfer laboratory protocols or deal with the subject in a rather superficial manner. Hence the idea to write a gene therapy textbook that is broad and comprehensive, but at the same time provides sufficient molecular and clinical detail to be of interest to students, professors, and specialists in the various disciplines that contribute to gene therapy. I have tried to keep the language plain and, whenever possible, non-technical. Since the book is intended to be a textbook in the field of gene therapy in both the basic science and clinical areas, whenever technical descriptions are required, they are provided.

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