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Human Apolipoprotein Mutants III

Diagnosis and Treatment

Springer Berlin,
139,09 € Lieferbar in 2-3 Tagen


Proceedings of the NATO Advanced Research Workshop on Human Apolipoprotein Mutants III. Apolipoproteins in the Diagnosis and Treatment of Disease, held at Limone sul Garda, Italy, April 5-8, 1992


Titel: Human Apolipoprotein Mutants III
Autoren/Herausgeber: Cesare Sirtori, Guido Franceschini, Bryan H.Jr. Brewer (Hrsg.)
Aus der Reihe: NATO ASI Series
Ausgabe: Softcover reprint of the original 1st ed. 1993

ISBN/EAN: 9783642846366

Seitenzahl: 291
Format: 23,5 x 15,5 cm
Produktform: Taschenbuch/Softcover
Gewicht: 475 g
Sprache: Englisch

Hopes to develop apolipoproteins for diagnostic or, even
better, therapeuticpurposes are growing. Areas of use may
range from arterial disease to AIDS, fertilization programs,
neurological or inflammatory disorders, and the like.
However, these young members of the large family of
circulating proteins still deserve careful study, both in
terms of structural and functional properties and of their
pathological changes. In addition, related molecules, in
particular belonging to the family of enzymes, such as
lipases and acyltransferases, offer exciting insight into
the mechanisms of regulation of lipid transport and
Described hereis the use of apolipoproteins and enzymes in
the diagnosis of coronary and cerebrovascular disease.
Structural and functional changes of apolipoproteins are
related to lipid transport and binding to different
receptors. Further, the development of apolipoprotein drugs
and their possible clinical use for vascular and non
vascular disease is discussed and finally an overview on
lipoprotein transformation processes, expression systems and
natural mutants is provided.

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