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Human Gametes and Preimplantation Embryos

Assessment and Diagnosis

Springer New York,
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This book surveys new and established methods for assessing gamete and embryo viability in assisted reproduction, covering best practices for selecting viable specimens and the spectrum of emerging adjunctive technologies for predicting reproductive potential.


Titel: Human Gametes and Preimplantation Embryos
Autoren/Herausgeber: David K. Gardner, Denny Sakkas, Emre Seli, Dagan Wells (Hrsg.)
Ausgabe: Softcover reprint of the original 1st ed. 2013

ISBN/EAN: 9781493942688

Seitenzahl: 306
Format: 25,4 x 17,8 cm
Produktform: Taschenbuch/Softcover
Gewicht: 618 g
Sprache: Englisch

In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates. Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of “omics” approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine. - Newsletter
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