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MAP Kinase Signaling Protocols

von
Humana Press,
Buch
176,54 € Lieferbar in 5-7 Tagen

Kurzbeschreibung

Exploring the activation and function of components of the MAPK signaling cascades, this volume presents fully updated techniques to study MAPK. Chapters include lists of the necessary materials, step-by-step laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Hauptbeschreibung

Titel: MAP Kinase Signaling Protocols
Autoren/Herausgeber: Rony Seger (Hrsg.)
Aus der Reihe: Methods in Molecular Biology
Ausgabe: 2nd ed. 2010

ISBN/EAN: 9781607617945

Seitenzahl: 529
Format: 25,4 x 17,8 cm
Produktform: Hardcover/Gebunden
Gewicht: 1,327 g
Sprache: Englisch

Mitogen-activated protein (MAP) kinase (MAPK) cascades are key signaling components that govern essentially all cellular processes evoked by any type of stimulation, and it has been well established that the malfunctioning of these cascades leads to various diseases including cancer, autoimmunity, and diabetes. In MAP Kinase Signaling Protocols, Second Edition, expert researchers fully update the popular first edition the key techniques used in the study of MAPK signaling cascades in various cellular contexts. This thorough volume explores essential topics such as activation and function of components of the MAPK signaling cascades, the study of MAPK cascades as transmitters of membranal receptor signals, structure-function relationships of MAPKs, studies on the regulation of MAPK cascades, the use of lower organisms, animal models, and human genetics in the study of MAPKs, as well as the study of MAPKs in specific systems and diseases. Written in the highly successful Methods in Molecular Biology™ series format, chapters includes introductions to their respective subjects, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Comprehensive and cutting-edge, MAP Kinase Signaling Protocols, Second Edition aims to facilitate the study of MAPKs and allow for quicker progress in our knowledge of many vital cellular processes as well as devastating diseases.

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