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Molecular Drug Properties

Measurement and Prediction

von
Wiley-VCH,
E-Book ( PDF mit Adobe DRM )
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Kurzbeschreibung

This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity,solubility, electronic properties and conformation.

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Autor

Titel: Molecular Drug Properties
Autoren/Herausgeber: Raimund Mannhold (Hrsg.)
Weitere Mitwirkende: Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Aus der Reihe: Methods and Principles in Medicinal Chemistry
Ausgabe: 1. Auflage

ISBN/EAN: 9783527621293

Seitenzahl: 472
Produktform: E-Book
Sprache: Englisch

Raimund Mannhold is Professor for Molecular Drug Research at the University of Düsseldorf, Germany. His scientific interests lie with QSAR studies and related methods to determine and predict drug properties. He is a founding editor of the book series 'Methods and Principles in Medicinal Chemistry' and serves on the editorial boards of several journals in the field of medicinal chemistry and drug design.

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