Instills a deeper understanding of how and why organicreactions happen
Integrating reaction mechanisms, synthetic methodology, andbiological applications, Organic Mechanisms gives organicchemists the tools needed to perform seamless organic reactions. Byexplaining the underlying mechanisms of organic reactions, authorXiaoping Sun makes it possible for readers to gain a deeperunderstanding of not only chemical phenomena, but also the abilityto develop new synthetic methods. Moreover, by emphasizingbiological applications, this book enables readers to master bothadvanced organic chemistry theory and practice.
Organic Mechanisms consists of ten chapters, beginningwith a review of fundamental physicochemical principles that areessential for understanding the nature of organic mechanisms. Eachone of the remaining chapters is devoted to a major class oforganic reactions, including:
* Aliphatic C-H bond functionalization
* Functionalization of the alkene C=C bond by cycloadditionreactions
* Nucleophilic substitutions on sp3-hybridized carbons
* Nucleophilic additions and substitutions on carbonylgroups
* Reactivity of the alpha-hydrogen to carbonyl groups
A brief review of basic organic chemistry begins each chapter,helping readers move from fundamental concepts to an advancedunderstanding of reaction mechanisms. Key mechanisms areillustrated by expertly drawn figures highlighting microscopicdetails. End-of-chapter problems enable readers to put theirnewfound knowledge into practice by solving key problems in organicreactions with the use of mechanistic studies, and a SolutionsManual is available online for course instructors.
Thoroughly referenced and current with recent findings inorganic reaction mechanisms, Organic Mechanisms isrecommended for upper-level undergraduates and graduate students inadvanced organic chemistry, as well as for practicing chemists whowant to further explore the mechanistic aspects of organicreactions.