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Pathogenesis and Treatment of Diabetes Mellitus

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In this book on diabetes mellitus both the pathogenesis and treat ment of the disease will be discussed. Pathogenetic studies have led to the distinction between type I and type II diabetes. In type I hyperglycaemia is due predominantly to insulin deficiency; in type II insulin resistance is more important. Three pathogenetic factors are thought to play a role in the etiol ogy of type I diabetes: heredity, viral infections and immunity. There may be a relationship between these three aspects since genetic pre disposition changes the susceptibility to viral infections and/or the immunological defence against these infections. Insulitis ensues. Auto immune processes initiated by this chain of events may contribute to the destruction of the B cells in the islets of Langerhans and diabetes -may eventually follow. This means that at the time of the sudden out break of the disease, the destructive process has already been active for years.


Titel: Pathogenesis and Treatment of Diabetes Mellitus
Autoren/Herausgeber: J.K. Radder, H.H.P.J. Lemkes, H.M.J. Krans (Hrsg.)
Ausgabe: 1986

ISBN/EAN: 9780898388282

Seitenzahl: 188
Format: 0 x 0 cm
Produktform: Hardcover/Gebunden
Gewicht: 550 g
Sprache: Englisch - Newsletter
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