A seminar on "Practical Approaches to Earthquake Prediction and Warning" was held in Tokyo and Tsukuba, Japan on November 7-11, 1983. This was the sixth seminar on earthquake prediction in the framework of the U.S.-Japan Cooperation in Science Program, a series that was initiated in 1964. The Japan Society for the Promotion of Science and the National Science Foundation of the U.S.A. sponsored the seminar. The U.S. Geological Survey gave substantial additional support by sen ding a number of scientists to the seminar. C. H. Scholz, Columbia University, and T. Rikitake, Nihon University, were the co-convenors on behalf of the U.S.A. and Japan, respectively. 23 Japanese and 23 American delegates and observers took part in the seminar. Forty papers were presented during the three days of scientific sessions at the Interna tional House of Japan, Roppongi, Tokyo, November 7-9. The other two days were spent on a field trip to Tsukuba Science City, where national laboratories engaged in earthquake prediction research and other aspects of earthquake hazard reduction have been established by several agencies of the Japanese Government. The program of the scientific sessions was organized according to the following topics: 1. The national programs of Japan and the U.S.A. 2. Theory and long-term earthquake prediction. 3. Strain and stress. 4. Observation systems. 5. Various precursors. 6. Social response, public policy and earthquake engineering.