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RNA Metabolism in Trypanosomes

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Springer Berlin,
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Based on recent research, this book covers important aspects of biosynthesis, processing and functions of RNA in trypanosomes, from transcription to RNA editing, mRNA splicing/translation/turnover, processing of transfer and ribosomal RNA and more.

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Titel: RNA Metabolism in Trypanosomes
Autoren/Herausgeber: Albrecht Bindereif (Hrsg.)
Aus der Reihe: Nucleic Acids and Molecular Biology
Ausgabe: 2012

ISBN/EAN: 9783642433252

Seitenzahl: 274
Format: 23,5 x 15,5 cm
Produktform: Taschenbuch/Softcover
Gewicht: 433 g
Sprache: Englisch

Trypanosomes are unicellular protozoa of ancient evolutionary origin that are responsible for several tropical diseases, such as African sleeping sickness. Over the last few decades, research in trypanosome biology has revealed many unique and fascinating features, many of which have helped to establish new paradigms in other biological systems. This applies in particular to studies in gene expression and regulation, which benefit enormously from the trypanosome genome projects and from the new genome-wide approaches recently introduced in trypanosome research. This volume covers the most important aspects of biosynthesis, processing, and functions of RNA in trypanosomes, ranging from transcription to RNA editing, mRNA splicing/translation/turnover, processing of transfer and ribosomal RNA, RNA interference, and current transcriptome-wide analyses. Recent progress in RNA-focused research in trypanosomatids promises to yield novel insights into trypanosome-specific features, as well as to reveal in the process new potential therapeutic strategies for combating these parasitic diseases.

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