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Ribosome-inactivating Proteins

Ricin and Related Proteins

Wiley, J,
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Kurzbeschreibung

This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain.

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Titel: Ribosome-inactivating Proteins
Autoren/Herausgeber: Fiorenzo Stirpe, Douglas Lappi (Hrsg.)
Ausgabe: 1. Auflage

ISBN/EAN: 9781118846940

Seitenzahl: 328
Produktform: E-Book
Sprache: Englisch

Fiorenzo Stirpe is Professor Emeritus at the Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.
Douglas A. Lappi is the President and Chief Scientific Officer of Advanced Targeting Systems, USA.

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