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The Long and Short Non-coding RNAs in Cancer Biology

von
Springer Singapore,
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Kurzbeschreibung

The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets.

Details
Schlagworte
Autor

Titel: The Long and Short Non-coding RNAs in Cancer Biology
Autoren/Herausgeber: Erwei Song (Hrsg.)
Aus der Reihe: Advances in Experimental Medicine and Biology
Ausgabe: 1st ed. 2016

ISBN/EAN: 9789811014963

Seitenzahl: 458
Format: 23,5 x 15,5 cm
Produktform: Hardcover/Gebunden
Gewicht: 859 g
Sprache: Englisch

Dr. Erwei Song is a professor at SunYat-Sen Memorial Hospital, Guangzhou, China.

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