A comprehensive look at the latest research findings andclinical applications of oncogenic viruses
Written by a panel of academic experts, Viral Oncology isthe first self-contained and comprehensive book to present bothscientific and clinical information on viruses linked to some ofthe most important human cancers. Readers can turn to this book forthe most in-depth and up-to-date coverage of: HPV-associatedcancers; molecular events associated with HPV-induced human cancer;the role of the HPV E6 oncoprotein in malignant progression; virusassociation with brain tumors; involvement of the polyomavirus JCVin colorectal cancer; possibleassociation of BKV with prostatecancer; oncogenic transformation bypolyomavirus large T antigen;SV40 and human cancer; SV40 and mesothelioma; molecular immunologyof hepatitis B-associated viral cancer; hepatitis B vaccineand hepatocellular carcinoma; pathogenesis of acute and chronichepatitis Cvirus infection; molecular mechanisms of hepatitis Cvirus-induced cellulartransformation; clinical aspects of HTLV-1associated cancer; oncogenic potential of the HTLV-1 tax protein;HIV-associated malignancy; HIV-related lymphoma; biology andepidemiology of HHV-8; the role of KSHV in pathogenesis ofKaposi'ssarcoma; molecular pathobiology of EBV infection; and EBVas a pathogen.
Several chapters are devoted to the basic science of oncogenicviruses for thestudy of their pathogenesis, drug development, andemployment of viral vectorsfor vaccine and gene therapy. The bookalso includes complementary clinically based chapters describingnatural courses and treatments. Additionally, bonusclinicalmaterials are embedded within chapters and an easy-to-useindexcompletes the book.
Viral Oncology is an essential resource for clinical andresearch oncologists in medical facilities and biological researchlaboratories; clinicians and scientists working in relatedbiomedical areas; medical students working toward a first or higherdegree in the life sciences and other biomedical fields; andpharmaceutical scientists and developers.